Search on: LEUKOTRIENE C 1 
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Descriptor English:   Leukotriene C4 
Descriptor Spanish:   Leucotrieno C4 
Descriptor Portuguese:   Leucotrieno C4 
Synonyms English:   Leukotriene C
Leukotriene C-1
Leukotriene C-4
Leukotriene C1
Leukotrienes C
Leukotriene C 1
Leukotriene C 4
LTC4  
Tree Number:   D10.251.355.255.100.450.855.455
D10.251.355.310.166.887.855.455
D23.469.050.175.450.725.400
Definition English:   The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990) 
Indexing Annotation English:   /biosyn /physiol permitted; DF: note short X ref
History Note English:   94; was see SRS-A 1983-93; LEUKOTRIENE C1 & LEUKOTRIENES C were see SRS-A 1983-93 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   31350 
Unique Identifier:   D017997 

Occurrence in VHL:
 

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